Comma+ING Modifier can modify the noun closest to it?

[yuxi19900219]

Neuroscientists, having amassed a wealth of knowledge over the past twenty years about the brain and its development from birth to adulthood, are now drawing solid conclusions about how the human brain grows and how babies acquire language.
(A) Neuroscientists, having amassed a wealth of knowledge over the past twenty years about the brain and its development from birth to adulthood, are
(B) Neuroscientists, having amassed a wealth of knowledge about the brain and its development from birth to adulthood over the past twenty
years, and are
(C) Neuroscientists amassing a wealth of knowledge about the brain and its development from birth to adulthood over the past twenty years, and are
(D) Neuroscientists have amassed a wealth of knowledge over the past twenty years about the brain and its development from birth to adulthood,
(E) Neuroscientists have amassed, over the past twenty years, a wealth of knowledge about the brain and its development from birth to adulthood,
OA: E
Here, I have a question about D explanation.
OG explains D: The final descriptor in present tense, now drawing conclusions ... does not fit the opening clause, which is in present-perfect tense (have amassed a wealth ...) and seems to modify adulthood.
I don't quite understand its explanation.
That is to say, the final descripter's tense must agree with the main clause'f tense ???? And the comma+ing modify the nearest noun rather than the whole sentence preceding it???
Can anybody help me ?

[tim]

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