I want to know about usage of 'having been done' and having done
Some patients who do not respond therapies of depression may simply have received inadequate treatment, having, for example been prescribed a drug as a dosage too low to be effective or having been taken off a drug too soon.
A -- having, for example been prescribed a drug as a dosage too low to be effective or having been
B -- having, for example, a drug prescription that was ineffective because the dosage was too low, or being
C -- as, for example, having too low of a dosage of prescribed drug for it to be effective, or being
D -- when they have, for example, been prescribed too low a drug dosage for it to be effective, or were
E -- for example, when they have a drug prescription with a dosage too low to be effective, or been